Formulation development and characterization of propranolol hydrochloride microballoons for gastroretentive floating drug delivery
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چکیده
منابع مشابه
Formulation and Evaluation of Floating Gastroretentive Drug Delivery System of Diltiazem Hydrochloride
The present investigation describes the design and evaluation of monolithic gastro retentive dosage forms of diltiazem. Hydrophilic cellulose derivatives, Sodium alginate, Sodium carboxy methyl cellulose, Polyox, Methocel K100M in combination with Methocel E6LV are used as the rate controlling polymers. Sodium bicarbonate was incorporated as gas generating agent. Tablets were prepared by employ...
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The objective of present investigation is to design a sustained release floating microballoons of Metformin HCl using two polymers of different permeability characteristics Cellulose Acetate Butyrate (MW of 16,000) and Eudragit RS 100 (MW of 150,000) using the oil-in-oil emulsion solvent evaporation method. The prepared microballoons were studied for drug release behavior in simulated gastric f...
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BACKGROUND AND THE PURPOSE OF THE STUDY The objective of the present work was to improve bioavailability of cepodoxime proxetil through gastroretentive microballoon formulation. METHODS Microballoons of cefpodoxime proxetil were formulated by solvent evaporation and diffusion method employing hydroxypropylmethyl cellulose (HPMC) and ethyl cellulose (EC) polymers and characterized for particle...
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The present investigation was aimed to formulate and evaluate the gastro-retentive floating microballoons of glipizide using hydrophilic polymers hydroxypropyl methylcellulose (HPMC) and Eudragit RS100 (RS 100) by emulsion solvent evaporation technique. The floating microballoons were evaluated using micromeritic properties, buoyancy, in vitro drug release, scanning electron microscopy and stab...
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ژورنال
عنوان ژورنال: African Journal of Pharmacy and Pharmacology
سال: 2011
ISSN: 1996-0816
DOI: 10.5897/ajpp11.525